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Epigenetic Regulation of the ERβ Gene on the Estrogen Signal Transfection Pathway in Colon Cancer Ce

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摘 要:We studied the regulatory effects of the estragen receptorβ(ERβ)gene on the downstream estrogen sign
  • 【题 名】Epigenetic Regulation of the ERβ Gene on the Estrogen Signal Transfection Pathway in Colon Cancer Cells
  • 【作 者】翟荣林 王国斌 蔡开琳 陶凯雄 许飞 张万里 王智勇
  • 【机 构】Department of General Surgery Union Hospital Tongji Medical College Huazhong University of Science and Technology
  • 【刊 名】《华中科技大学学报:医学英德文版》2010年 第1期 -页 共6页
  • 【关键词】
  • 【文 摘】We studied the regulatory effects of the estragen receptorβ(ERβ)gene on the downstream estrogen signal transfection pathway in colon cancer cells and the possible mechanisms involved.A human ERβ gene recombinant expression plasmid,pEGFP-C1-ERβ,was constructed and transfected into the Caco-2 colon cancer cell line,a line with low ERβ gene expression.The expression of ERβ mRNA and protein was detected 72h after transfection.RT-PCR was used to examine the expression levels of the progesterone recepror(PR)gene ...
 
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