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Reduction in Bile Acid Pool Causes Delayed Liver Regeneration Accompanied by Down-regulated Expressi

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摘 要:The present study attempted to examine the effects of bile acid pool size on liver regeneration afte
  • 【题 名】Reduction in Bile Acid Pool Causes Delayed Liver Regeneration Accompanied by Down-regulated Expression of FXR and C-Jun mRNA in Rats
  • 【作 者】董秀山 赵浩亮 马晓明 王世明
  • 【机 构】The First Hospital of Shanxi Medical University
  • 【刊 名】《华中科技大学学报:医学英德文版》2010年 第1期 -页 共6页
  • 【关键词】
  • 【文 摘】The present study attempted to examine the effects of bile acid pool size on liver regeneration after hepatectomy.The rats were fed on 0.2% cholic acid(CA)or 2% cholestyramine for 7 days to induce a change in the bile acid size,and then a partial hepatectomy(PH)was performed.Rats fed on the normal diet served as the controls.Measurements were made on the rate of liver regeneration,the labeling indices of PCNA,the plasma total bile acids(TBA),and the mRNA expression of cholesterol 7alpha-hydroxylase(CYP7A1),...
 
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