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Melatonin Protects N2a against Ischemia/Reperfusion Injury through Autophagy Enhancement

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摘 要:Researches have shown that melatonin is neuroprotectant in ischemia/reperfusion-mediated injury.Alth
  • 【题 名】Melatonin Protects N2a against Ischemia/Reperfusion Injury through Autophagy Enhancement
  • 【作 者】国艳春 王剑飞 王忠强 杨易 王西明 段秋红
  • 【机 构】Department of Biochemistry and Molecular Biology School of Basic Medical Sciences Tongji Medical College Huazhong University of Science and Technology Department of Emergency Medicine Wuhan General Hospital of Guangzhou Command
  • 【刊 名】《华中科技大学学报:医学英德文版》2010年 第1期 -页 共7页
  • 【关键词】
  • 【文 摘】Researches have shown that melatonin is neuroprotectant in ischemia/reperfusion-mediated injury.Although melatonin is known as an effective antioxidant,the mechanism of the protection cannot be explained merely by antioxidation.This study was devoted to explore other existing mechanisms by investigating whether melatonin protects ischemia/reperfusion-injured neurons through elevating autophagy,since autophagy has been frequently suggested to play a crucial role in neuron survival.To find it out,an ischemia/...
 
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